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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LATS1 All Species: 18.79
Human Site: T1012 Identified Species: 29.52
UniProt: O95835 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95835 NP_004681.1 1130 126870 T1012 K A H P F F K T I D F S S D L
Chimpanzee Pan troglodytes XP_001173355 1130 126853 T1012 K A H P F F K T I D F S S D L
Rhesus Macaque Macaca mulatta XP_001090321 809 89257 D692 D G H I K L T D F G L C T G F
Dog Lupus familis XP_534537 1097 121903 A978 N G A D D L K A H P F F G A I
Cat Felis silvestris
Mouse Mus musculus Q8BYR2 1129 126167 T1011 K A H P F F K T I D F S S D L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506215 1121 123969 V1002 K A H P F F K V I D F S S D L
Chicken Gallus gallus XP_419666 1136 127431 T1018 K A H P F F K T I D F S S D L
Frog Xenopus laevis NP_001087838 1118 125984 S998 K V H P F F K S I D F S S D L
Zebra Danio Brachydanio rerio NP_001018346 1068 120780 F950 E I K A Q P F F R T I D L S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA38 1105 122470 L988 H I P P Q A E L S R E A T D L
Honey Bee Apis mellifera XP_395146 1137 124999 K1020 E G M D L I L K L C V G A D R
Nematode Worm Caenorhab. elegans Q2L6W9 476 55529 C359 K A T I K R F C C E A E R R L
Sea Urchin Strong. purpuratus XP_795100 1199 133231 F1081 L D I K S H P F F Q T I D L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53894 756 86927 S639 F P D D I H I S Y E A E D L I
Red Bread Mold Neurospora crassa P38679 598 67999 D481 R H S L Y F P D D I T L G V D
Conservation
Percent
Protein Identity: 100 99.6 35.8 50.9 N.A. 92.8 N.A. N.A. 80.8 85.2 74.7 63.1 N.A. 38.6 40.2 20.7 38
Protein Similarity: 100 99.8 44.7 63.4 N.A. 96.7 N.A. N.A. 87.1 92.1 83.4 73.7 N.A. 50.2 52.6 29.6 51.9
P-Site Identity: 100 100 6.6 13.3 N.A. 100 N.A. N.A. 93.3 100 86.6 0 N.A. 20 6.6 20 0
P-Site Similarity: 100 100 13.3 20 N.A. 100 N.A. N.A. 93.3 100 93.3 6.6 N.A. 40 26.6 26.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28 24.4
Protein Similarity: N.A. N.A. N.A. N.A. 42.3 35.5
P-Site Identity: N.A. N.A. N.A. N.A. 0 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 40 7 7 0 7 0 7 0 0 14 7 7 7 0 % A
% Cys: 0 0 0 0 0 0 0 7 7 7 0 7 0 0 0 % C
% Asp: 7 7 7 20 7 0 0 14 7 40 0 7 14 54 14 % D
% Glu: 14 0 0 0 0 0 7 0 0 14 7 14 0 0 0 % E
% Phe: 7 0 0 0 40 47 14 14 14 0 47 7 0 0 7 % F
% Gly: 0 20 0 0 0 0 0 0 0 7 0 7 14 7 0 % G
% His: 7 7 47 0 0 14 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 14 7 14 7 7 7 0 40 7 7 7 0 0 14 % I
% Lys: 47 0 7 7 14 0 47 7 0 0 0 0 0 0 7 % K
% Leu: 7 0 0 7 7 14 7 7 7 0 7 7 7 14 54 % L
% Met: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 7 7 47 0 7 14 0 0 7 0 0 0 0 0 % P
% Gln: 0 0 0 0 14 0 0 0 0 7 0 0 0 0 0 % Q
% Arg: 7 0 0 0 0 7 0 0 7 7 0 0 7 7 7 % R
% Ser: 0 0 7 0 7 0 0 14 7 0 0 40 40 7 0 % S
% Thr: 0 0 7 0 0 0 7 27 0 7 14 0 14 0 0 % T
% Val: 0 7 0 0 0 0 0 7 0 0 7 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _